UTILIZING DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING (DCE-MRI) TO ANALYZE INTERSTITIAL FLUID FLOW AND TRANSPORT IN GLIOBLASTOMA AND THE SURROUNDING PARENCHYMA IN HUMAN PATIENTS

Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients

Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy.Limited access of drugs to tumor cells is one reason for such grim clinical outcomes.A driving force for therapeutic delivery is interstitial fluid flow (IFF), both within the tumor and in the surrounding brai

read more


The study of establishment of an in vivo tumor model by three-dimensional cells culture systems methods and evaluation of antitumor effect of biotin-conjugated pullulan acetate nanoparticles

In this study, three-dimensional (3D) hydrogels were used for human hepatocellular carcinoma (HepG2) cells culture systems in vitro and establishment of an in vivo xenografted tumor model.Based on our previous work on the biotin-conjugated pullulan acetate nanoparticles (Bio-PA NPs) raceline renegade 8 16x10 as anticancer drug carriers, we further

read more

Perforator flap for burn reconstruction

Background: Majority of burn patients in Bangladesh are treated at home and tend to develop scar and scar contracture.Other than physical limitations there are also stigmatization, loss of marriageability or divorce particularly for women.Skin grafts are prone to contraction and need prolonged splintage and physiotherapy.Flaps are often too bulky.L

read more

Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression

Abstract Background DNA methylation plays important biological roles in plants and animals.To examine the rice genomic methylation landscape and assess its functional significance, we generated single-base resolution DNA methylome maps for Asian cultivated rice Oryza sativa ssp.japonica, indica and their wild relatives, Oryza rufipogon and Oryza ni

read more